珞珈講壇第304講預(yù)告

時　間：2019年10月14日（周一）16：00

地　點：武漢大學(xué)櫻頂老圖書館

主講人：嚴(yán)加安 中國科學(xué)院院士

題　目：我心目中的科學(xué)與藝術(shù)

主講人簡介：

中科院數(shù)學(xué)與系統(tǒng)科學(xué)研究院研究員，1999年當(dāng)選中國科學(xué)院院士。1993年獲國家自然科學(xué)二等獎，2002年應(yīng)邀在第24屆國際數(shù)學(xué)家大會上作45分鐘報告，2006年獲何梁何利基金科技進步獎，2007年獲華羅庚數(shù)學(xué)獎，2010年當(dāng)選為國際數(shù)理統(tǒng)計學(xué)會會士（Fellow）。

Brief Introduction of Professor Yan Jiaan

Yan Jiaan, a researcher at the Institute of Mathematics and Systems Science, Chinese Academy of Sciences, was elected as a member of the Chinese Academy of Sciences in 1999. In 1993, he was awarded the second prize of National Natural Science. In 2002, he was invited to give a 45-minute lecture at the 24th International Congress of Mathematicians. In 2006, he won the Ho Leung Ho Lee Foundation Prize for Scientific and Technological Progress. In 2007, he was awarded the Hua Luogeng Prize for Mathematics. In 2010, he was elected as a fellow of the International Society of Mathematical Statistics.

珞珈講壇第305講預(yù)告

時　間：2019年10月16日（周三）15：00

地　點：武漢大學(xué)櫻頂老圖書館

主講人：James Naismith 英國皇家科學(xué)院院士

題　目：A Chemical View of Enzymatic Transformations

主講人簡介：

James Naismith教授是英國皇家科學(xué)院院士，牛津大學(xué)結(jié)構(gòu)生物學(xué)系結(jié)構(gòu)生物學(xué)教授,哈維爾研究中心主任(Research Complex at Harwell)，羅瑟琳富蘭克林研究中心主任(Rosalind Franklin Institute)。曾擔(dān)任英國圣安德魯斯大學(xué)生物大分子科學(xué)中心主任，在圣安德魯斯大學(xué)任職期間曾為該中心的規(guī)劃導(dǎo)向、建設(shè)運營和經(jīng)費申請做出過不可磨滅的貢獻。

在他的研究生涯里，他長期利用結(jié)構(gòu)生物學(xué)手段解析蛋白結(jié)構(gòu)，同時偶聯(lián)分子生物學(xué)與生物化學(xué)手段，攻克生物機制與疾病靶點。其中包括生物信號傳導(dǎo)、蛋白分子與底物互作模式、病原微生物糖基組裝、病毒復(fù)制、特殊天然產(chǎn)物生物合成等領(lǐng)域。發(fā)表論文包括Nature、Science、Cell在內(nèi)的頂級學(xué)術(shù)論文220余篇。在他的科研生涯里曾獲得多種個人獎項用于表彰其對其研究領(lǐng)域做出的突出貢獻。

2005年Jim教授當(dāng)選愛丁堡皇家科學(xué)院院士（FRSE），2014年當(dāng)選英國皇家科學(xué)院院士（FRS），2016年當(dāng)選美國科學(xué)進步學(xué)院院士（AAAS）。在過去的12年里，其中的8年他均以首席身份職位，在擔(dān)任CCP4項目首席中他曾2次為該項目成功延續(xù)經(jīng)費，曾帶領(lǐng)英國結(jié)構(gòu)生物學(xué)進入歐洲X射線自由電子激光器線站計劃，并被選為該線站國際用戶聯(lián)合首席。

Brief Introduction of Professor James Naismith

James Naismith is Fellow of Royal Society, Professor of Structural Biology at the University of Oxford, Director of the Research Complex at Harwell and Director designate of the Rosalind Franklin Institute. Before he came to Oxford, he was the Deputy of Biomolecular Science Research Complex at University of St. Andrews. During that time, he drove the vision, wrote the grant, secured University and Wellcome Trust funding for the Biomolecular Science Research Complex and oversaw its design, construction and delivery.

During his research career, he is focusing at the application of protein structure determination by X-ray crystallography coupled to molecular biology and biochemistry to probe biological mechanisms and to target specific disease pathways. He has ongoing research in 1) signal transduction 2) physical basis of protein carbohydrate interactions 3) pathogenic bacteria glycan assembly 4) viral replication 5) the biosynthesis of unusual natural products. Until now, he has published more than 220 papers in top journals including Nature Science and Cell. In 2000, he received Carbohydrate Chemistry Prize from Royal Society of Chemistry, in 2001, he got Leverhulme Trust Molecular Biology Prize and in 2004 he received Corday-Morgan Medal, in 2004, he was awarded the Colworth Medal from Royal Society of Chemistry, in 2009, he got Jeremy Knowles Medal, in 2012 he won Rita & John Cornforth Award. At last but not least, in 2014, he was awarded with Royal Society Wolfson Research Merit Award.

He was elected as Fellowship of the Royal Society of Edinburgh in 2005. He was elected as Membership of EMBO in 2009, Fellowship of the Academy Medical Sciences in 2012, Fellowship of the Royal Society in 2014 and Fellow of American Association for Advancement of Science in 2016. For over 12 years, 8 years Chairman he was heavily involved in running CCP4. He twice wrote and successfully renewed funding for the project. He managed both the strategic and operational aspects of the entire suite. He has led the UK structural biology into the European X-FEL. He is the elected head of the International User Consortium for this beamline.