時 間：2018年5月21日（周一）10:00

地 點(diǎn)：武漢大學(xué)櫻頂老圖書館

主講人：David W. Christianson 美國賓夕法尼亞大學(xué)教授

題 目：Structural Biology and Chemistry of Histone Deacetylases in Human Disease and Drug Discovery

主講人簡介：

David W. Christianson教授于哈佛大學(xué)先后獲得了學(xué)士、碩士以及博士學(xué)位，并在隨后的28年時間內(nèi)在賓夕法尼亞大學(xué)化學(xué)系開展學(xué)術(shù)研究。David W. Christianson教授長期致力于金屬依賴性脫乙酰酶，精氨酸酶和萜類生物合成酶等酶的結(jié)構(gòu)與功能的研究。迄今為止，已成功在Science，Nature，Nature Structural & Molecular Biology，JACS，PNAS，Nature Communication等多個國際頂級期刊上發(fā)表一系列重要的科學(xué)論文。

他的成就使其獲得了眾多獎項(xiàng)，包括美國化學(xué)學(xué)會頒發(fā)的輝瑞酶學(xué)化學(xué)獎和生物學(xué)過程化學(xué)Repligen獎，哈佛大學(xué)拉德克利夫高級研究學(xué)院的Elizabeth S.和Richard M. Cashin研究員以及哈佛大學(xué)化學(xué)與化學(xué)生物學(xué)客座教授。

Brief Introduction of Professor David W. Christianson

Professor David W. Christianson received the AB, AM, and PhD from Harvard University before moving to the University of Pennsylvania, where he has been a member of the faculty for 28 years. His current research focuses on structural and function of metal-dependent arginases, deacetylases, and enzymes of terpenoid biosynthesis. At present, he had published series of papers in top professional journals suchas Science,Nature, Nature Structural & Molecular Biology, JACS, PNAS, Nature Communication.

His accomplishments have been recognized by numerous awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, and Fellowships from the John Simon Guggenheim Memorial Foundation, the Radcliffe Institute for Advanced Study at Harvard University, and the visiting Professor of Chemistry and Chemical Biology of Harvard University.